It would take 3 hours 18 mins to go from Houston to and 2 hours 39 mins to go from Pearlington to Lafayette. The major city closest to the halfway point between Houston, TX and Pearlington, MS is Lafayette, LA, situated 217 miles from Houston, TX and 159 miles from Pearlington, MS. It would take 2 hours 50 mins to go from Houston to Egan and 3 hours 3 mins to go from Pearlington to Egan. The closest town to the halfway point is Egan, LA, situated 186 miles from Houston, TX and 186 miles from Pearlington, MS. The population was 1,684 at the 2000 census. It is part of the GulfportBiloxi, Mississippi Metropolitan Statistical Area. Route 90, along the Pearl River, at the Louisiana state line. This location is 185.94 miles away from Houston, TX and Pearlington, MS and it would take approximately 2 hours 53 mins to reach the halfway point from both locations. Pearlington is a census-designated place (CDP) in Hancock County, Mississippi, United States, on U.S. If you want to meet halfway between Houston, TX and Pearlington, MS or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 30.246962 and -92.485741, or 30º 14' 49.0632' N, 92º 29' 8.6676' W. Halfway Point Between Houston, TX and Pearlington, MS The total driving distance from Houston, TX to Pearlington, MS is 370 milesor 595 kilometers.